Shanghai, China (SportsNetwork. Discount Hydro Flask .com) - Top-seeded reigning two-time champion Novak Djokovic and former world No. 1 Roger Federer reached the third round, while former top-ranked great Rafael Nadal was sent packing Wednesday at the $4 million Shanghai Masters tennis event. Playing with a bout of appendicitis this week, the second-seeded Nadal lost his second straight match, this time in 6-3, 7-6 (8-6) fashion at the hands of fellow Spanish left-hander Feliciano Lopez. Nadal also came up a quarterfinal loser last week at the China Open, his first tournament back after missing three months of action with a right wrist injury. For sure [I dont feel] perfect, said Nadal. Its the same way that I felt before. A little bit more dizzy now. But thats it. Nothing that I have to worry about. When you lose a match, it is not the moment to talk about obvious things. I lost. Feli played better than me. Nadal, who has been taking antibiotics for the appendicitis, began feeling pain in his abdomen on Saturday, and the next day went to a hospital where he learned he had the early stages of the condition. Nadal said he opted for antibiotics rather than undergo surgery right away. The French Open champion said the risk of his condition getting any worse after a few days of steady improvement is always very, very low. The 2009 Shanghai runner-up said he will talk with his doctors when he returns to Spain about whether hell need to have the appendix removed. Meanwhile, the current world No. 1 Djokovic handled Austrian Dominic Thiem 6-3, 6-4 and the third-seeded Federer barely survived against Argentine Leonardo Mayer, 7-5, 3-6, 7-6 (9-7), in 2 hours, 42 minutes, as Mayer led 5-2 in the third-set tiebreak before the Swiss legend fought back to advance at Qizhong Forest Sports City Arena. The 2010 Shanghai runner-up Federer saved five match points on Wednesday. It was the second-most match points he has saved in his career. Federer saved seven match points in a first-round win over Scott Draper in Cincinnati in 2003. Djokovic is undefeated in his last 11 matches in Shanghai and is looking to lift the trophy here for the third year in a row. Already a Masters winner in Indian Wells, Miami and Rome this season, the 27-year-old star is chasing his 20th Masters title. He dismantled Tomas Berdych for the China Open championship last week. Djokovic beat Juan Martin del Potro in last years Shanghai finale. Another top-five upset came when former top-10 Frenchman Gilles Simon foiled fourth-seeded Australian Open champ Stan Wawrinka, 5-7, 7-5, 6-4, on Day 4. And American Jack Sock posted a big upset by tackling seventh-seeded U.S. Open runner-up Kei Nishikori 7-6 (7-5), 6-4. The Japanese star Nishikori was fresh off his titles in Tokyo and Kuala Lumpur and had won 15 of his previous 16 matches on tour. Eleventh-seeded former world No. 1 Andy Murray continued his recent run of fine play by besting 6-foot-8 Pole Jerzy Janowicz 7-5, 6-2. Murray captured his first title in 15 months on Shenzhen, China, two weeks ago and was a semifinalist in Beijing last week. Murray titled here in Shanghai in 2010 and 2011 and was the runner-up in 2012. In other action involving top-10 seeds, No. 5 David Ferrer overcame Slovak Martin Klizan 4-6, 7-6 (7-4), 6-4; a No. 6 Berdych drubbed Frenchman Richard Gasquet 6-3, 6-1; Argentine wild card Juan Monaco doused No. 8 Canadian Milos Raonic 5-2, retired; and Frenchman Julien Benneteau upended No. 10 Grigor Dimitrov 7-5, 6-3. Raonic was last weeks Tokyo runner-up to Nishikori. Also on Wednesday, 13th-seeded John Isner edged out fellow American Steve Johnson 7-6 (8-6), 7-6 (9-7); 14th-seeded Spaniard Roberto Bautista Agut outlasted Canadian Vasek Pospisil 7-6 (7-1), 3-6, 6-4; Tunisian qualifier Malek Jaziri beat Chinese wild card Chuhan Wang 6-0, 6-4; and Russian Mikhail Youzhny snuck past Croat Ivan Dodig 7-6 (9-7), 6-7 (4-7), 6-3. The third round will be staged on Thursday, as Djokovic will face Kazakhstans Mikhail Kukushkin, Federer will meet Bautista Agut, and the 2011 Shanghai runner-up Ferrer will tangle with the resurgent Murray in some featured matches. This weeks big winner will collect $798,450. Hydro Flask Sale . Mired in an offensive slump, Lowry - the NBAs leader in taking charges this season - did what he has learned to do best, standing his ground and drawing a crucial offensive foul on the Cavaliers all-star point guard. Fast forward 30 seconds to the Cavs next possession, with the home team still trailing by three, Spencer Hawes - one of the leagues best passing big men - threw an interception, intended for Tyler Zeller and picked off by DeMar DeRozan. Cheap Hydro Flask Free Shipping . The 27-year-old forward has informed the Leafs that he will be unable to play in Monday nights home game against the Columbus Blue Jackets. http://www.discounthydroflaskcheap.com/ . Belfort was originally schedule to fight Chris Weidman at UFC 173 on May 24, but a Nevada State Athletic Commission ban on testosterone replacement therapy forced the former light heavyweight champ to withdraw.With the NHL Draft coming up on June 27 and free agency opening on July 1, discussions between NHL general managers are heating up towards a busy off-season. Each day, TSN.ca provides the latest rumours, reports and speculation from around the NHL beat. Going D-eep Ordinarily, one would assume the Edmonton Oilers were once again in prime position to improve their future, holding the third overall pick in Fridays NHL Draft. Trading down, however, might be the best course of action for the Oil - according to The Hockey News Matt Larkin. Larkin suggests that with the Florida Panthers likely to make Aaron Ekblad the first-overall pick on Friday, Edmonton would be better served to trade down from the No. 3 to acquire "an established asset" and scoop the Drafts consensus second-best blueliner, Red Deers Haydn Fleury. The Oilers have long needed to bolster their blue line and started that process by taking Darnell Nurse seventh overall last June. Larkin floats the hypothetical idea of the Oilers looking to deal with the Toronto Maple Leafs, possibly getting a young defender like Jake Gardiner along with the eighth overall selection in exchange for the third overall pick. The scenario would offer the Leafs a crack at a top-end forward like one of Sam Reinhart, Sam Bennett or Leon Draisaitl while allowing the Oilers to have a realistic shot at Fleury. Wait and C? From the sounds of it, the Montreal Canadiens may not be searching for a new captain come July 1? ESPN The Magazines Craig Custtance tweeted Saturday morning that Habs captain Brian Gionta will be meeting with his agent to discuss his future options. Cheap Hydro Flask Sale. According to Giontas agent Steve Bartlett, Gionta has "no strong inclination to leave" Montreal. A pending unrestricted free agent, Gionta is coming off a five year deal that paid him $5 million per season. The 35-year-old American scored 18 goals and 22 assists in 81 games last season. Foreign Markets Teams may look beyond North American shores on July 1 to scoop up additions for the 2014-15 season. In another tweet, Custance mentioned a couple intriguing options could be returning to the NHL, namely Kontinental Hockey League forward Leo Komarov and former first-round pick Peter Mueller. Custance mentioned that Komarov is still talking to his former team, the Toronto Maple Leafs. The Leafs hold Komarovs NHL rights until July 1 since he opted to return to the KHL for 2013-14 while still eligible for restricted free agency in the NHL. The Finn has spent parts of each of the last five seasons with Moscow Dynamo, including a brief stint during the lockout-shortened 2012-13 season. Komarov was a popular grinder and depth forward for the 2012-13 Leafs team that became the first to make the playoffs since 2003-04. Mueller, meanwhile, led the Swiss League in goals in 2013-14. He scored 24 in 49 games with Kloten. The eighth overall selection by the Phoenix Coyotes in 2006, Muellers NHL career-high was 22 goals in his 2007-08 rookie season. China NFL Jerseys Cheap Nike NFL Jerseys NFL Jerseys Cheap Wholesale NFL Jerseys Cheap Basketball Jerseys Online Stitched Hockey Jerseys Wholesale Baseball Jerseys Football Jerseys Outlet College Jerseys For Sale Cheap MLB Jerseys Wholesale Soccer Jerseys Wholesale Jerseys For Sale Wholesale NFL Jerseys ' ' '