Two East Division leaders will meet at Fenway Park on Monday when the American League's Boston Red Sox (74-33) take on the National League's Philadelphia Phillies (58-47) as solid home favorites. The Red Sox will be looking to extend their three-game winning streak Bert Blyleven Jersey , while the Phillies hope to end a three-game skid after dropping three of four to the Cincinnati Reds on the weekend. MLB betting line: The Red Sox opened as -155 favorites (wager $155 to win $100); the total is at nine runs, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)MLB betting pick, via OddsShark computer: 4.0-3.6, Red Sox (MLB picks on every game)Check out the OddsShark podcast on iTunes or at OddsShark.libsyn.com for more odds information, betting picks and a breakdown of this week's top sports betting news. Why the Phillies can pay on the MLB linesPhiladelphia may have been caught looking ahead to this interleague series in getting outscored 16-6 in the last three games at Cincinnati. The Phillies had won three in a row prior to their losing streak, and they should be primed to rebound with All-Star Aaron Nola (12-3, 2.42 ERA) on the hill. The 25-year-old righty has not earned a win since July 9 but has not pitched poorly in his last two starts, allowing five runs and nine hits in 11 innings with three walks and 10 strikeouts. Nola is 4-3 on the road this year with a 2.86 ERA but has limited opposing batters to a .190 average in 11 outings away from home. Why the Red Sox can pay on the MLB linesBoston is the best team in baseball right now, and it is not even close. Whether the Red Sox can maintain this sizzling pace remains to be seen, but they are a force to be reckoned with for the time being.Opposing Nola will be former AL Cy Young Award winner David Price (11-6, 4.17), who is coming off one of his best starts of the season. Carlos Osorio/Associated PressThe 32-year-old southpaw blanked the Detroit Tigers for 6.1 innings on July 20, scattering four hits with one walk and five strikeouts. Price did throw 14 pitches in a suspended game on Wednesday to follow it up, but that should not affect him here.Smart betting pickBoston has dominated interleague play over the past year, going 18-2 in its last 20 games against NL foes. Coincidentally, one of the two losses came at Philadelphia 1-0 on June 15, 2017. The Phillies are 9-4 in their previous 13 interleague games, which is pretty solid as well, and they will have the better pitcher on the mound. Take Philly.MLB betting trendsThe total has gone over in eight of Philadelphia's last 11 games.Boston is 13-2 in its last 15 games at home.Boston is 7-1 in its last eight games when playing Philadelphia. All MLB odds and betting trends according to Bleacher Report's official odds partner, OddsShark. Check out OddsShark on Twitter and Instagram or head to YouTube for more betting picks and analysis on this week's top games. You can also download the free odds tracker app. Ah, baseball. The sport where a 162-game schedule that spans six calendar months is somehow still not enough to crown a champion in two of the six divisions.The Chicago Cubs and Milwaukee Brewers will square off at Wrigley Field to determine the NL Central champion, while the Los Angeles Dodgers and Colorado Rockies will meet at Dodger Stadium with the NL West title on the line.The winners of those games will advance on to the NLDS, with the NL Central champion holding the No. 1 seed and the NL West winner taking on the Atlanta Braves as the No. 2 seed.The losersof those games will turn around and play each other on Tuesday in the NL Wild Card Game.For a look at the current postseason bracket, head over toMLB.com.So while the full playoff seeding has not yet taken shape, it's never too early for some bold predictions on how the 2018 postseason will play out.Wild Card GamesJ.A. HappJim McIsaac/Getty ImagesWhile the NL wild-card matchup is still up in the air http://www.yankeesfanproshop.com/authentic-paul-o_neill-jersey , the AL game on Wednesday will feature the New York Yankees hosting the Oakland Athletics.The Yankees won 100 games during the regular season, but still finished eight games back in the AL East, so they find themselves in the winner-take-all Wild Card Game for the second year in a row as a result.Playing that extra game didn't stop them from advancing to the ALCS a year ago, and the upstart Athletics will have their hands full with a lineup that set an MLB record with 267 home runs.Oakland does not have a lockdown starter to call on for the Wild Card Game, but they do have one of the best bullpens in baseball, with the veteran trio of Jeurys Familia, Fernando Rodney and Blake Treinen slamming the door in the late innings.If the Yankees can strike early, they'll be in good shape.Prediction: Yankees advance to ALDSDivision SeriesMaddie Meyer/Getty ImagesHere's where we need to make some predictions on how at least one NL division plays out.We'll say the Dodgers beat the Rockies later today, clinching the No. 2 seed in the process and a meeting with the Atlanta Braves in the NLDS.Regardless of who winds up as the NL Central champ, there's a good chance the Cubs and Brewers will meet up again in the NLDS, as they finished the regular season with the two best records in the National League.In other words, sorry Rockies.The Cubs have the postseason track record and they won the season series (11-8, +6 run differential), but this Brewers team is built for October.They have the hottest hitter on the planet and likely NL MVP in Christian Yelich anchoring the lineup, and while the starting rotation isn't flashy, their bullpen is excellent. Jeremy Jeffress, Josh Hader and Corey Knebel are as good a late-inning trio as any in baseball, while Brandon Woodruff and Corbin Burnes are both multi-inning weapons.Cubs fans won't want to hear it, but Brewers advance.Meanwhile, the Dodgers starting pitching has been lights out over the past month, with Clayton Kershaw (6 GS, 3-0, 3.89 ERA), Walker Buehler (5 GS, 1-1 Jacoby Ellsbury Jersey , 1.95 ERA) and Hyun-Jin Ryu (5 GS, 3-2, 1.50 ERA) and Rich Hill (5 GS, 5-0, 3.90 ERA) all hitting their stride.That, coupled with a bullpen that has seen the pieces fall into place as the season has progressed, will be enough for the Dodgers to advance to the NLCS for the third year in a row.On the AL side, the Cleveland Indians and Houston Astros matchup up extremely well with two stacked starting rotations.The Indians will trot out Corey Kluber (20-7, 2.89 ERA, 222 K), Trevor Bauer (12-6, 2.21 ERA, 221 K), Carlos Carrasco (17-10, 3.38 ERA, 231 K) and Mike Clevinger (13-8, 3.02 ERA, 207 K) as they look to avenge last year's ALDS exit.The Astros will counter with Justin Verlander (16-9, 2.52 ERA, 290 K), Gerrit Cole (15-5, 2.88 ERA, 276 K), Charlie Morton (15-3, 3.13 ERA http://www.yankeesfanproshop.com/authentic-don-mattingly-jersey , 201 K) and Dallas Keuchel (12-11, 3.74 ERA, 153 K).The Astros have a superior bullpen (3.03 ERA vs. 4.60 ERA), so advantage Houston in a series where runs could be at a premium.And that leaves us with a Red Sox vs. Yankees matchup.The Red Sox won the season series by a slim 10-9 margin, but the Yankees took two series in September, so the momentum would seem to be on their side.Mookie Betts and J.D. Martinez have shouldered the run production load all season for the Red Sox, while the Yankees have relied on different players at different times, including a red-hot Luke Voit.The X-factor in this matchup will be the Yankees starting pitching. The trio of J.A. Happ, Masahiro Tanaka and Luis Severino can be excellent when they pitch up to their potential, but they've all been inconsistent at times this year.Behind the lefty duo of Chris Sale and David Price, and an offense that is firing on all cylinders, the Red Sox move on to the ALCS.Prediction: Dodgers and Brewers advance in NL; Red Sox and Astros advance in ALChampionship SeriesChristian YelichDylan Buell/Getty ImagesThe Brewers have made the playoffs just five times in franchise history.The Dodgers have made the playoffs six years in a row and 34 times in a storied franchise history that includes six World Series titles.Call it David vs. Goliath.And yet, it's still hard to not see a little bit of the 2015 Kansas City Royals in this year's Brewers team, and we've seen time and again that strong defense and lights out pitching can go a long way in October.Brewers advance to the World Series for just the second time in team history.Meanwhile, the AL matchup is more like Goliath vs. Goliath.The Red Sox wrapped up the regular season with the best record in baseball, but the Astros are the defending champs for a reason, and this year's team has a better rotation and a deeper bullpen than last year's squad.This one is a prime candidate to go seven games鈥攋ust like last year's ALCS鈥攁nd the Astros have to be the favorites to advance to the World Series once againPrediction: Brewers and Astros advance.World SeriesAlex BregmanTom Szczerbowski/Getty ImagesThe storybook season ends here for the Brewers.Don't expect a sweep, but the Astros are simply the better team, and that would be the case when stacked up against any of the NL contenders.Not since the 2000 Yankees has a team repeated as World Series champs, but this year's Astros team checks all the boxes.Just for kicks, let's say Alex Bregman puts a bow on his breakout season by taking home World Series MVP honors.Prediction: Astros in sixAll stats courtesy of Baseball Reference, unless otherwise noted.